Drug Discovery with Privileged Building Blocks

Product Description 
Drug Discovery with Privileged Building Blocks traces back PharmaBlock’s founding philosophy of designing privileged building blocks. High-quality building blocks are crucial not only to biological activities of different molecules but also to ADMET properties, which eventually will impact the success rate of drug discovery projects. A thorough study of how building blocks perform in drug molecules and a regular analysis of new building block structures in the latest researches have proven to be a fruitful strategy to generate novel building blocks. Using this strategy, PharmaBlock has supplied the drug industry with a great number of building blocks, which are increasingly being adopted by drug hunters, and these are identified in this book. 
Each chapter may be read and studied without learning the previous chapters. This book will be a good starting point for novice medicinal chemists, and veteran medicinal chemists will find it useful as well. 
Key Feature\nThe book covers privileged building blocks appearing most frequently on patents for novel drugs.\nThe latest relevant tactics are explained in the context of drug design and medicinal chemistry.\nKey synthesis, especially large-scale synthesis, is described.\nThe most recent literature references are cited.\nAbout the Author 
Dr. Jie Jack Li is an established chemist with over 20 years of experience in both medicinal chemistry and process chemistry. He is also widely published as an author or co-author of 34 peer-reviewed articles, 12 patents, and 29 books. Prior to joining ChemPartner, Dr. Li worked at Pfizer, BMS, and Revolution Medicines in oncology, antivirals, metabolic disease, CNS, anti-inflammatory, and dermatology, targeting enzymes, receptors, or ion channels. Dr. Li was also a professor at the University of San Francisco for four years, teaching organic and medicinal chemistry. He earned his Ph.D. from Indiana University and was a post-doctoral fellow at MIT. 
Dr. Minmin Yang received his PhD in organic synthesis from Auburn University, US in 2001, and did post-doctoral training at the same school from 2002 to 2004. Prior to founding PharmaBlock, he worked with increasing responsibilities from group leader to section head of medicinal chemistry at Roche Palo Alto and Roche China for 4 years. Dr. Yang has authored 80 publications, including 16 international patents.

Drug Discovery with Privileged Building Blocks: Tactics in Medicinal Chemistry

Science & Math

Li, Jie Jack

Yang, Minmin

Chemistry

CRC Press

Drug Discovery with Privileged Building Blocks traces back PharmaBlock’s founding philosophy of designing privileged building blocks. High-quality building blocks are crucial not only to biological activities of different molecules but also to ADMET properties, which eventually will impact the success rate of drug discovery projects. A thorough study of how building blocks perform in drug molecules and a regular analysis of new building block structures in the latest researches have proven to be a fruitful strategy to generate novel building blocks. Using this strategy, PharmaBlock has supplied the drug industry with a great number of building blocks, which are increasingly being adopted by drug hunters, and these are identified in this book. 
Each chapter may be read and studied without learning the previous chapters. This book will be a good starting point for novice medicinal chemists, and veteran medicinal chemists will find it useful as well. 
Key Feature 
The book covers privileged building blocks appearing most frequently on patents for novel drugs. 
The latest relevant tactics are explained in the context of drug design and medicinal chemistry. 
Key synthesis, especially large-scale synthesis, is described. 
The most recent literature references are cited.

See the best price to sell, buy, or rent books by Li, Jie Jack. BookScouter helps to compare book prices from 25+ online bookstores and 30+ buyback vendors with a single search.

Books by Li, Jie Jack

See the best price to sell, buy, or rent books by Li, Jie Jack. BookScouter helps to compare book prices from 25+ online bookstores and 30+ buyback vendors with a single search.

Drug Discovery with Privileged Building Blocks: Tactics in Medicinal Chemistry

Drug Discovery with Privileged Building Blocks